More than 100 million such medicines itimes are prescribed annually in the USA. Paracetamol overdose is the leading reason of irreversible damage of a liver. It becomes the reason of 42 thousand hospitalizations and more than 400 fatal cases in the USA annually.
Experts also have recommended FDA to lower the maximum dose of paracetamol in over the counter preparations, such as, Panadol, Theraflu and others, from 500 to 325 milligram's, and to establish the maximum daily dose within 4 000 milligram's. Thus the consultative group has voted against limiting of quantity of tablets of paracetamol in one packing.
According to law FDA is not obliged to follow recommendations of expert group, however in most cases they are carried out, so in the near future it is necessary to expect interdictions and restrictions.
Paracetamol is extremely popular in the USA - in 2005 in the country has been sold 28 billion tablets containing it, that is just about of one dose for four days on each citizen of the country.
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